Retrospective cohort study on the prevalence of severe obesity and the impact on treatment outcomes in knee and hip arthroplasty patients using data from the Dutch Arthroplasty Register
Approval date: November 25th 2025
I. van Donkelaar, M Scheurwater, E Jerry, S Nienhuijs, P de Baat, L Dekker, D van Veghel, R van Kempen
Research proposal abstract
This retrospective cohort study of real-world data aims to examine the national prevalence of severe obesity (BMI ≥35 kg/m²) among adult patients undergoing knee or hip arthroplasty in the Netherlands. Additionally, our objective is to investigate the impact of severe obesity on clinical outcomes of arthroplasties in the Netherlands. Data will be derived from the Dutch Arthroplasty Register (LROI) covering the period from 2014 to 2024. Patients aged ≥18 years with registered BMI values who underwent a knee or hip arthroplasty will be included.
Outcomes include revision rates, functional outcomes and quality of life. Among those who undergo early revision, we will assess the reasons for revision and stratify these by BMI categories to evaluate the association between severe obesity and revision indications.